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Verapamil blocks the voltage- calcium channels and decreases the amount of Ca2 + in the cytoplasm. For relief of hypertensive crises intravenous diazoxide, a clone-Din, azameton, labetalol, sodium nitroprusside, nitroglycerin. The total coronary sieving flow (by 90% by the lumen of small coronary vessels) with little change.A sieving of coronary blood in favor of ischemic area. With systematic use of nitroglycerin to it quickly develops addictive, primarily reduces sieving side effects, particularly headache. In the initial stage of arterial hypertension hypertension is associated with increased tone of the sympathetic nervous system, leads to an increase in cardiac output and narrowing of blood vessels. In this case, blood pressure, but lower efficiency which reduce the influence sympathetic nervous system (the central action of antihypertensive drugs-action, blockers). But even if this fails, you should remove arterial hypertension, since hypertension contributes to the development Hairy Cell Leukemia atherosclerosis, multiple sclerosis, angina pectoris, myocardial infarction, heart failure, visual disturbances, and disorders of the kidneys. Adverse effects of nitroglycerin related to its vasodilating action. In all cases, seek to cure the underlying disease. Believe that patients with hypertension antihypertensive average properties should be applied systematically, warning high blood pressure. If ingestion (bioavailability about 100%) duration of up to 12 hours of myocardial infarction is introduced intravenously. Organic long-acting nitrates are used mainly to prevent strokes. Reduction in blood pressure may be accompanied by tachycardia, dizziness, tinnitus, possible orthostatic hypotension. The compounds of this group are similar in structure and action of nitroglycerin. Antihypertensives known drugs, which are expressed Snee blood pressure. Because of expansion and pulsation sieving cerebral vessels may be throbbing headache, sometimes very strong. Thus, when receiving nitroglycerin under the tongue may be hyperemia of face, neck, feeling the heat. Decreases the binding of Ca2 + from troponin C and is facilitated by inhibition troponintropomiozina influence on the interaction of actin and myosin. As a result of increased Right Lower Lobe-lung pressure. Can be effective for angina, but in some patients worsens due to «steal here Myocardial infarction sieving usually accompanied by very strong pain in the heart, cardiac arrhythmias, heart failure, and lower blood pressure. Frequent cause of hypertension may be a delay in the body of sodium in connection with excessive consumption salt and the lack of natriuretic factors. Since a decrease in blood filling the heart chambers tension is reduced to walls, reduced extravasal compression of coronary vessels and improves coronary blood flow. Isosorbide mononitrate - a drug of the active metabolite of isosorbide dinitrate. Mechanism of negative inotropic action verapamipa. Isosorbide dinitrate (Nitrosorbid) ingestion (Bioavailability 22%) is 46 h (tabletkiretard - 12h). With various diseases of the causes of hypertension are different. In particular, expanding collateral vessels, that connect large subepicardial arteries with arteries subendokarda. To a lesser extent lower blood pressure and less likely to cause headaches. Pheochromocytoma was removed surgical-logical way, but before surgery, during surgery or if surgery is not possible, reduce blood pressure by means of osadrenoblokatorov. Therefore, hypertension Diuretics are often used, can remove excess sodium from the body.